Effects on birds: Bensulide is only slightly toxic to birds. The bensulide herbicide, Betasan, was fed to adult Japanese quail for 3 weeks, and egg hatchability was significantly reduced at the highest dose (about 50 mg/kg/day), but fertility was not affected. Blood cholinesterase was inhibited at lower doses, but recovered within 2 weeks after the treatments stopped. The oral LD50 in bobwhite quail is 1386 mg/kg .
Effects on aquatic organisms: link is moderately to highly toxic to aquatic organisms, including rainbow trout and bluegill. The LC50 for bensulide is 1.1 mg/L in rainbow trout, 1.4 mg/L in bluegill, and 1 2 mg/L in goldfish. The compound is moderately toxic to aquatic invertebrates like the amphipod Gammarus lacustrus. The calculated bioconcentration is low and it is not expected to bioaccumulate.
Effects on other organisms: link is very highly toxic to bees. The LD50 of bensulide is 0.0016 mg per bee.