Nate and Chuck! She's more close to them than to Dan! that's even if they are together (1x17 someone??).. But Nate most i think..

Probably not, but I'm picking him anyway bitches.

Nate or Chuck. Not sure. It's more complicated with Nate because of their fillings and history so that's why im picking Chuck

I'm not choosing between Nate and Dan. lol

clearly, theyve been friends for like ever rite?

Probably not, but I'm picking him anyway bitches.

well it could be Chuck too.. i would say it's Chuck waaaaaaay more than Dan :D

Chuck or Nate.
They've all been friends for like ever!
she only met dan when she was 16 (or was she 17 ?:P)
so defenetly one of them. And what we saw in the 1x09 flashback episode im guessing blaie/nate/serena where a bit closer then chuck

I've always thought she was closest to Dan, even when they were going out they had such a close bond friendship wise and that never changed after they broke up, she often ends up running to him because he will always be there for her and she knows it.

and Nate

Or Chuck